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However, if these vasodilators enter the systemic circulation, they could contribute to ME/CFS symptoms such as fatigue, flu-like symptoms, pain, fever, and sleep disturbances, similar to the effects observed when vasodilators spill over in dysmenorrhea (346)
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Additionally, the episode delves into emerging strategies for specifically augmenting REM sleep, including temperature regulation and a new class of sleep medications that target the brain's orexin/hypocretin system
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