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Se is known to contribute to several crucial physiological functions in mammals: antioxidant defense, fertility, thyroid hormone metabolism, and immune response (Hadaszadeh and Beggs, 2006
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Parkinsonism can be caused by other agents such as metoclopra mide, methyldopa, and reserpine (all reversible and dose-dependent), in addition to the meperidine analog, MPTP, that can cause irreversible parkinsonism in intravenous drug abusers
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