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In addition, in animal models of diabetic retinopathy, ASTX preserved histological and functional outcomes of the diseases, increasing the levels of antioxidant enzymes, and reducing levels of oxidative mediators, such as NF-κB and aldolase reductase activity [108]
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Research from the National Cancer Institute has documented several potential mechanisms by which IV vitamin C may affect cancer cells: Phase I clinical trials at medical institutions including the University of Iowa and Thomas Jefferson University have demonstrated safety and potential benefits when HDIVC is administered alongside standard chemotherapy for various cancer types
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