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Examples include longitudinal investigations of telomerase-associated pathways, telomere-maintenance mechanisms, transcription-associated signaling processes, circadian regulatory systems, and other studies involving multiple sampling timepoints

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Tyrosinase activity becomes apparent during anagen III, pigment transfer from hair bulb melanocytes to cortical keratinocytes is initiated during anagen IV and active melanogenesis continues throughout anagen V and VI, ceasing with the onset of catagen